growth

Growth: 1984-1992

Guided by a group of distinguished trustees appointed after Howard Hughes' death, the Institute began a period of rapid expansion in 1984. Drawing on the financial resources provided from the sale of the Hughes Aircraft Company, the Institute established itself as a driving force in biomedical research and science education. A grants program established in 1987 has become the largest private effort to improve science education in the United States. Hughes investigators have been lauded as the most productive and influential in biomedical research.

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1984

Since Mr. Hughes did not name a successor trustee, the Delaware Court of Chancery designates eight prominent citizens as trustees of the Institute; they meet for the first time on May 29.

The National Institutes of Health and HHMI plan a research training program for medical students to be called the HHMI-NIH Research Scholars Program.

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1985

During the process of selling the Hughes Aircraft Company, the trustees reaffirm the Institute's status as a medical research organization, thereby declining to transform it into a private foundation.

Purnell Choppin, M.D.
The trustees elect Purnell W. Choppin, M.D., as vice president and chief scientific officer.

A groundbreaking ceremony is held for Hughes House.

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1986

HHMI transfers administrative functions from Florida to Maryland.

A formal research program is established in structural biology.

An Informational Forum on the Human Genome is held at NIH.

The first issue of the periodical publication Research in Progress is published, reporting the research of the 100 Hughes investigators.

William T. Quillen, Esq., a former justice of the Supreme Court of Delaware, is elected vice president and general counsel.

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1987

HHMI Site
An Affiliated Investigator Program begins, facilitating appointment of scientists beyond the large laboratory units the Institute has traditionally supported. HHMI can now "support the best scientists where we find them," according to a public announcement.

HHMI resolves a long-standing disagreement with the Internal Revenue Service.

New officers and trustees join HHMI.

Purnell W. Choppin, M.D. is elected president.

HHMI announces that it will begin awarding grants for science education related to biomedical research.

HHMI purchases 22.5 acres in Chevy Chase, Maryland, for a headquarters and conference center. The site is just outside Washington, D.C., not far from NIH. Construction is to begin in 1991.

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1988

An architectural and construction team for the headquarters is announced.

W. Maxwell Cowan, M.D., Ph.D., provost of Washington University, is elected vice president and chief scientific officer.

Under the new grants program, the first HHMI Predoctoral Fellowships in the Biological Sciences are awarded to 60 outstanding young men and women to study at 21 universities. Sixty (later increased to 80) fellowships will be awarded each year.

The Undergraduate Biological Sciences Education Program supports liberal arts and historically black colleges.

Under the Research Resources Program, Cold Spring Harbor Laboratory receives a $7 million, three-year grant to support its postgraduate training courses in neuroscience and structural biology. A $4 million grant goes to the Marine Biological Laboratory at Woods Hole, Massachusetts, to support its library and its education and training programs in the biological sciences.

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1989

At midyear, HHMI employees number more than 1,600, including 184 independent investigators at 37 U.S. universities, hospitals, and academic medical centers.

HHMI and General Motors Corporation reach a new agreement concerning GM stock acquired as part of the 1985 sale of the aircraft company.

The Institute awards $61 million to 51 universities; HHMI begins awarding Research Training Fellowships for Medical Students.

Thomas Cech
Investigator Thomas R. Cech, Ph.D., at the University of Colorado shares the Nobel Prize in Chemistry. Dr. Cech discovered that RNA can act as an enzyme.

Investigator Francis Collins, M.D., Ph.D., at the University of Michigan and colleagues in Toronto identify the gene that is defective in cystic fibrosis.

Recognizing the importance of maintaining safe work places for the Institute's investigators and other employees working in its laboratories, HHMI creates the Office of Laboratory Safety.

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1990

The Institute makes the first awards in its program of Postdoctoral Research Fellowships for Physicians.

The Human Genome Organisation (HUGO) receives a $1 million grant from HHMI. HUGO's purpose is to coordinate the international effort to map and sequence all human genes.

The Institute begins publishing a series of reports on biomedical science for a general audience. The first report, Finding the Critical Shapes, is on structural biology. High school and college biology students are a principal audience.

Irving S. Shapiro, Esq., is elected chairman of the Trustees, succeeding Dr. Thorn.

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1991

The neuroscience program is expanded to include cognitive neuroscience, the study of higher mental processes such as memory and learning.

The Institute steps into the international arena in Canada and Mexico.

The cornerstone of the new headquarters is unveiled at a ceremony on November 5 at the construction site in Chevy Chase.

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1992

The Institute announces five-year grants under its Precollege and Public Science Education Program.

Edwin Krebs, M.D., HHMI senior investigator emeritus at the University of Washington, shares the Nobel Prize in Physiology or Medicine.

José E. Trías, Esq., formerly a partner in the firm of Paul, Weiss, Rifkind, Wharton & Garrison, is elected vice president and general counsel, succeeding Mr. Quillen.

At the close of the fiscal year (August 31), the Institute's investments are valued at $6.57 billion.

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